TY - JOUR AU - Bragaglio, Andrea AU - Braghieri, Ada AU - Napolitano, Fabio AU - De Rosa, Giuseppe AU - Riviezzi, Amelia Maria AU - Surianello, Francesca AU - Pacelli, Corrado PY - 2015/02/02 Y2 - 2024/03/28 TI - Omega-3 supplementation, milk quality and cow immune-competence JF - Italian Journal of Agronomy JA - Ital J Agronomy VL - 10 IS - 1 SE - Original Articles DO - 10.4081/ija.2015.611 UR - https://www.agronomy.it/agro/article/view/ija.2015.611 SP - 9-14 AB - This study aimed to assess the effect of a dietary supplementation rich in n-3 fatty acids from algae (<em>Schizochytrium</em> <em>sp</em>.) on cow immune-competence and milk quality. Twenty-one lactating Italian Friesian cows (at 220±20 days of lactation) were equally allocated to 3 treatments: group C received no supplementation, group D was offered 136 g of docosahexaenoic acid (DHA) per day and group E was supplemented with 136 g of DHA + 2000 U.I. of vitamin E per day. Individual milk production was recorded weekly and samples were collected for analysis of milk composition and fatty acid profile. At the end of the trial and 2 weeks later animals were subcutaneously injected with 5 mg of keyhole limpet haemocyanin (KLH), whereas at the end of the trial and 8 weeks later skinfold thickness was measured after intradermal injection with 500 mg phytohaemagglutinin. Dietary treatment showed no effect on milk production. Concentrations of DHA were higher (P&lt;0.05) in milk fat from D and E groups, whereas polyunsaturated fatty acids tended to be higher (P&lt;0.10). When DHA and DHA + vitamin E were supplemented to the animals, milk sensory properties were significantly modified as samples from groups D and E could be discriminated from the control using the triangle test (P&lt;0.001). Both supplemented groups showed evidence of increased antibody response 4 to 8 weeks after the first KLH administration (P&lt;0.05). In the two skin tests the treated groups showed a higher skin thickening in comparison with control animals (P&lt;0.05). Although provided in a late stage of lactation, an n-3 fatty acid enriched diet favourably changed milk fatty acid profile and promoted animal healthiness by enhancing cellular and humoral immune response. ER -